Nano-niosome particles loaded with deferoxamine for management of iron overload complications
نویسندگان
چکیده
منابع مشابه
Sequential Deferoxamine - Deferasirox in Treatment of Major Thalassemia with Iron Overload
Abstract Background Iron overload is a major problem in patients with major thalassemia. An effective and safe iron chelator protocol with high compliance rate plays an important role in treatment of these patients. This study was done to assess the efficacy and safety of the sequential deferoxamine and deferasirox protocol in major thalassemia patients in Khuzestan province, Iran. Material ...
متن کاملEffects of deferasirox-deferoxamine on myocardial and liver iron in patients with severe transfusional iron overload.
Deferasirox (DFX) monotherapy is effective for reducing myocardial and liver iron concentrations (LIC), although some patients may require intensive chelation for a limited duration. HYPERION, an open-label single-arm prospective phase 2 study, evaluated combination DFX-deferoxamine (DFO) in patients with severe transfusional myocardial siderosis (myocardial [m] T2* 5-<10 ms; left ventricular e...
متن کاملsequential deferoxamine - deferasirox in treatment of major thalassemia with iron overload
abstract background iron overload is a major problem in patients with major thalassemia. an effective and safe iron chelator protocol with high compliance rate plays an important role in treatment of these patients. this study was done to assess the efficacy and safety of the sequential deferoxamine and deferasirox protocol in major thalassemia patients in khuzestan province, iran. material and...
متن کاملSafety and efficacy of subcutaneous bolus injection of deferoxamine in adult patients with iron overload.
We compared 48-hour urinary iron excretion after a twice-daily subcutaneous bolus injection of deferoxamine and after 12 hours of subcutaneous continuous infusion of the drug in 27 patients with iron overload (mean age, 55.7 years). In most patients, the iron overload was due to multiple transfusions administered during chemotherapy or as part of supportive care for a hematologic or oncologic d...
متن کاملsynthesis of amido alkylnaphthols using nano-magnetic particles and surfactants
we used dbsa and nano-magnetic for the synthesis of amido alkylnaphtols.
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.02187